Medicinal Chemistry: A Molecular and Biochemical Approach by Thomas Nogrady, Donald F. Weaver
Medicinal Chemistry: A Molecular and Biochemical Approach by Thomas Nogrady, Donald F. Weaver PDF, ePub eBook D0wnl0ad
Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource.Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered.
There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.
From reader reviews:
Patricia Lopez:
What do you regarding book? It is not important along with you? Or just adding material when you really need something to explain what your own problem? How about your spare time? Or are you busy person? If you don't have spare time to do others business, it is make you feel bored faster. And you have extra time? What did you do? Everyone has many questions above. They need to answer that question because just their can do which. It said that about guide. Book is familiar in each person. Yes, it is suitable. Because start from on kindergarten until university need this kind of Medicinal Chemistry: A Molecular and Biochemical Approach to read.
Hilton Rogers:
Reading can called head hangout, why? Because while you are reading a book specially book entitled Medicinal Chemistry: A Molecular and Biochemical Approach your thoughts will drift away trough every dimension, wandering in every single aspect that maybe not known for but surely might be your mind friends. Imaging just about every word written in a book then become one web form conclusion and explanation which maybe you never get previous to. The Medicinal Chemistry: A Molecular and Biochemical Approach giving you a different experience more than blown away the mind but also giving you useful details for your better life with this era. So now let us present to you the relaxing pattern at this point is your body and mind will likely be pleased when you are finished studying it, like winning a game. Do you want to try this extraordinary spending spare time activity?
Paula Salas:
You may spend your free time to see this book this reserve. This Medicinal Chemistry: A Molecular and Biochemical Approach is simple to create you can read it in the playground, in the beach, train as well as soon. If you did not get much space to bring often the printed book, you can buy the e-book. It is make you quicker to read it. You can save the actual book in your smart phone. Thus there are a lot of benefits that you will get when you buy this book.
Read Medicinal Chemistry: A Molecular and Biochemical Approach by Thomas Nogrady, Donald F. Weaver for online ebook
Medicinal Chemistry: A Molecular and Biochemical Approach by Thomas Nogrady, Donald F. Weaver Free PDF d0wnl0ad, audio books, books to read, good books to read, cheap books, good books, online books, books online, book reviews epub, read books online, books to read online, online library, greatbooks to read, PDF best books to read, top books to read Medicinal Chemistry: A Molecular and Biochemical Approach by Thomas Nogrady, Donald F. Weaver books to read online.
Tidak ada komentar:
Posting Komentar